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The
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    The
    Binding of Isaac Gameplay
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    The Binding of Isaac
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    The Binding of Isaac
    Video Game
The Binding of Isaac 100% Walkthrough [HD] [#01] - The first Playthrough
31:18
The Binding of Isaac 100% Walkthrough [HD] [#01] - The first Playthrough
210.8K viewsMar 11, 2012
YouTubeTheKuskus23
THE BINDING OF ISAAC REBIRTH Full Gameplay Walkthrough with All Endings - No Commentary Longplay
5:52:46
THE BINDING OF ISAAC REBIRTH Full Gameplay Walkthrough with All Endings - No Commentary Longplay
76K viewsOct 3, 2022
YouTubeRabidRetrospectGames
The Binding of Isaac: Rebirth - Gameplay Walkthrough Part 1 - Isaac First Run (PC)
49:17
The Binding of Isaac: Rebirth - Gameplay Walkthrough Part 1 - Isaac First Run (PC)
3.2M viewsNov 5, 2014
YouTubeZackScottGames
Beginner's Guide to the Binding of Isaac
56:02
Beginner's Guide to the Binding of Isaac
143K views3 months ago
YouTubeAnother Matt Playing Isaac
The Binding of Isaac: Repentance+ Online Gameplay 🌐 PS5 - Multiplayer fun
6:41
The Binding of Isaac: Repentance+ Online Gameplay 🌐 PS5 - Multiplayer fun
55 views2 days ago
YouTubeVideo Chums 🎮😄
The Binding of Isaac: Repentance+ - Nintendo Switch 2 Gameplay
25:23
The Binding of Isaac: Repentance+ - Nintendo Switch 2 Gameplay
4 views2 days ago
YouTubeContraNetwork
The Binding of Isaac: Afterbirth - Gameplay Walkthrough Part 1 - Isaac Hard Mode (PC)
1:03:01
The Binding of Isaac: Afterbirth - Gameplay Walkthrough Part 1 - Isaac Hard Mode (PC)
479.7K viewsNov 1, 2015
YouTubeZackScottGames
54:34
The Binding of Isaac: Afterbirth+ - Gameplay Walkthrough Part 1 - Apollyon vs. ??? (Afterbirth Plus)
365.9K viewsJan 4, 2017
YouTubeZackScottGames
1:44:02
The Binding of Isaac: Repentance - Gameplay Walkthrough Part 1 - Lazarus Without Dying!
205.1K viewsApr 1, 2021
YouTubeZackScottGames
1:06:14
EVERY ITEM IS EXPERIMENTAL TREATMENT - The Binding Of Isaac Challenge
3.8K views3 days ago
YouTubeSinvicta
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Short videos

31:18
The Binding of Isaac 100% Walkthrough [HD] [#01] - The first Playthrough
210.8K viewsMar 11, 2012
YouTubeTheKuskus23
5:52:46
THE BINDING OF ISAAC REBIRTH Full Gameplay Walkthrough with All Endings -
76K viewsOct 3, 2022
YouTubeRabidRetrospectGames
49:17
The Binding of Isaac: Rebirth - Gameplay Walkthrough Part 1 - Isaac First Run (PC)
3.2M viewsNov 5, 2014
YouTubeZackScottGames
56:02
Beginner's Guide to the Binding of Isaac
143K views3 months ago
YouTubeAnother Matt Playing Isaac
6:41
The Binding of Isaac: Repentance+ Online Gameplay 🌐 PS5 - Multiplayer fun
55 views2 days ago
YouTubeVideo Chums 🎮😄
25:23
The Binding of Isaac: Repentance+ - Nintendo Switch 2 Gameplay
4 views2 days ago
YouTubeContraNetwork
1:03:01
The Binding of Isaac: Afterbirth - Gameplay Walkthrough Part 1 - Isaac Hard Mode (PC)
479.7K viewsNov 1, 2015
YouTubeZackScottGames
54:34
The Binding of Isaac: Afterbirth+ - Gameplay Walkthrough Part 1 - Apollyon
365.9K viewsJan 4, 2017
YouTubeZackScottGames
1:44:02
The Binding of Isaac: Repentance - Gameplay Walkthrough Part 1 - Lazarus
205.1K viewsApr 1, 2021
YouTubeZackScottGames
1:06:14
EVERY ITEM IS EXPERIMENTAL TREATMENT - The Binding Of
3.8K views3 days ago
YouTubeSinvicta
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