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STEMI: From Occlusion to Reperfusion & Outcomes Event: Coronary plaque rupture → thrombosis → vessel occlusion → transmural ischemia (ST-elevation). Treatment: Immediate primary PCI (angioplasty) to restore flow. Post-PCI Spectrum: 1. Optimal: TIMI 3 flow, ECG normalization. 2. Stunned Myocardium: Patent artery with persistent T-wave inversion. 3. Residual Disease: Critical residual stenosis (e.g., 99%) causing angina at rest. 4. Managed Stenosis: Significant residual stenosis (e.g., 80%) with s

In patients with STEMI and multivessel disease, PCI for nonculprit lesions is superior to culprit lesion treatment alone. Whether an FFR-guided approach results in better clinical outcomes than an angiography-guided approach for complete revascularization is unclear. https://nej.md/36PxyKc | The New England Journal of Medicine