Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic tangles overwhelm normal repair pathways, cells flip on a fast but error-prone ...

Breakthroughs, discoveries, and DIY tips sent six days a week. Terms of Service and Privacy Policy. In 1976, workers excavating a tunnel for the Toronto subway system ...

Johnson and Alistar competed as finalists in CU Boulder’s 2025 Lab Venture Challenge where their technology generated much interest from industry leaders. Access to DNA is crucial in many branches of ...

For decades, scientists believed that DNA strands under stress would form knots, tangling into chaotic shapes. But new research led by the University of Cambridge shows otherwise: when put under ...

Plectonemes are the analog of the twisted tangles of telephone cords, and can form in DNA that is pulled through a nanoscale channel. They are called plectonemes. They are the analog of the twisted ...

They are called plectonemes. They are the analog of the twisted tangles of telephone cords, and can form in DNA that is pulled through a nanoscale channel. This is the finding of a study led by Ulrich ...

This landmark study describes the structure of the human RAD51 filament with a recombination intermediate called the displacement loop (D-loop). Using cryogenic structural, biochemical, and ...

Researchers reveal DNA strand separation demands greater mechanical force in realistic cellular environments, reshaping understanding of genetic processes and molecular interactions. Credit: Stock ...

Most biochemistry labs that study DNA isolate it within a water-based solution that allows scientists to manipulate DNA without interacting with other molecules. They also tend to use heat to separate ...

Most biochemistry labs that study DNA isolate it within a water-based solution that allows scientists to manipulate DNA without interacting with other molecules. They also tend to use heat to separate ...

DNA strand displacement circuits are inching closer to becoming cellular machines. Scientists are finding ways to make these programmable nanodevices stable and functional inside living cells. If ...

King Abdullah University of Science & Technology (KAUST)Mar 19 2025 For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event for DNA ...