BACKGROUND: Genetic variants in components or regulators of the RAS-MAPK signaling pathway are causative for severe and early-onset hypertrophic cardiomyopathy (HCM) in patients with Noonan syndrome ...

Iron deficiency anaemia is a blood condition that occurs when the body doesn’t produce enough red blood cells. It’s the most common type of anaemia worldwide, with around four million people in the UK ...

Gordon A. Brown, DO, FACOS, gives an overview of PTEN biology, distinctions between PTEN loss and deficiency, and the clinical importance of PI3K/AKT pathway activation in prostate cancer progression.

The complement system plays a vital role in the immune response against tuberculosis (TB), aiding in the recognition and clearance of Mycobacterium tuberculosis. However, its imbalance can result in ...

The FDA added a boxed warning to capecitabine and 5-FU labels, noting the risk of serious adverse reactions or death in patients with complete DPD deficiency. According to the safety alert, patients ...

1 Postgraduation Program in Health Sciences: Gynecology and Obstetrics, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil. 2 Department of Gynecology and Obstetrics, Faculty of ...

Complement 3 glomerulopathy (C3G) is a rare kidney disease that is also considered an autoimmune disorder. There is no single cure for C3G, but several treatments may slow disease progression, protect ...

FDA Fast Track designation has been granted to CTx001 for Geographic Atrophy secondary to Age-related Macular Degeneration CTx001 is an investigational AAV-based gene therapy designed to modulate ...

Please provide your email address to receive an email when new articles are posted on . A quality improvement initiative resulted in a sixfold increase in iron deficiency screening among pregnant ...