Genome editing using designer nucleases such as transcription activator-like effector nucleases (TALENs) or clustered regularly interspersed short palindromic repeats (CRISPR)-Cas9 nucleases is an ...

Digital PCR (dPCR) is a specialized approach to nucleic acid detection and quantification that is not reliant on standard curves. Instead, the quantity or numbers of molecules present in a reaction is ...

Murine viruses and bacteria can both confound experimental results and compromise the health status of laboratory mouse colonies. Such infectious agents can be introduced into colonies via ...

Thermo Fisher Scientific has produced another short, animated video featuring some very basic information about the polymerase chain reaction, PCR, one of the most common techniques in genetic ...

The gold standard for gene-expression analysis, qPCR, has been extensively studied. Standard protocols have been published and multiple instruments for cycling with real-time detection are ...

Designing reproducible PCR assays involves optimizing multiple moving targets, from standardizing each component in sometimes minute reaction volumes to planning ahead to ensure long-term and secure ...