Linear mixed models are increasingly used for the analysis of genome-wide association studies (GWAS) of binary phenotypes because they can efficiently and robustly account for population ...

Figure 1: Genetic liability estimates and P-values for PheWAS phenotypes. Table 1 PheWAS phenotypes associated with SNP variation in the HLA region*. Full size table Genes within the HLA region ...

Limitations of linear regression applied on ecological data -- Things are not always linear : additive modeling -- Dealing with heterogeneity -- Mixed effects modeling for nested data -- Violation of ...

In the early 1970s, statisticians had difficulty in analysing data where the random variation of the errors did not come from the bell-shaped normal distribution. Besides normality, these traditional ...