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生物通
8 个月
基于PKM2+凋亡囊泡递送的辛伐他汀-人参皂苷Rh2脂质体佐剂(LIPO-SIM-Rh2 ...
为解决疫苗佐剂种类有限且作用机制单一的问题,研究人员开发了辛伐他汀(SIM)与人参皂苷Rh2共载脂质体佐剂(LIPO-SIM-Rh2)。通过动物实验证实该佐剂能显著提升抗OVA特异性IgG滴度,激活MHC-I分子抗原呈递通路,促进树突细胞(DCs)归巢,且无显著器官毒性,为新型 ...
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