科学家们在细菌中发现了一种不依赖任何核酸模板，仅凭蛋白质自身的精密结构就能合成特定DNA序列的全新聚合酶。这一发现不仅打破了教科书中的经典法则，更拓展了人类对酶催化极限的认知边界。

In this valuable study, the authors develop new approaches to investigate mRNA imprinting, a phenomenon in which RNA-protein complexes form in the nucleus to influence the fate of transcripts in the ...

Opportunities lie in the expanding demand for protein therapeutics driven by chronic disease prevalence, advancements in cell-free systems, and personalized medicine. Growth is supported by companies ...

This study characterizes several novel activities of SARS-CoV-2 helicase nsp13, providing valuable insights into potentially new functions of this essential RNA-processing enzyme in the virus life ...

A study on how aging impacts the brain in killifish has found that getting old selectively impairs the production of some key DNA- and RNA-binding proteins. And this change contributes to hallmarks of ...

Nerve cells have amazing strategies to save energy and still perform the most important of their tasks. Researchers from the University Hospital Bonn (UKB) and the University of Bonn as well as the ...

A principle of DNA synthesis that has dominated biology textbooks for decades could be upended. An enzyme has been discovered ...

A novel study uncovers how a subtle chemical tweak transforms the naturally occurring phytotoxin into a powerful molecular glue, 12-deoxyfusicoccin (12-dFC), that locks 14-3-3 proteins onto the ...

Learn how messenger RNA, spike protein, and lipid nanoparticles drive rapid advances in vaccines and cancer therapies, reshaping modern medicine with precision and speed. Pixabay, spencerbdavis1 ...

Cases of Borna disease virus 1 (BoDV-1) are extremely rare in humans, but in those who develop disease, the outcome is severe ...