These models can be used either offline to provide the optimal process cycle, or online to provide optimal, real-time process control [3]. This is the target of the iREMO project (www.iremo.eu), an EC ...

In a recent article, a U.K. group outlined their vision for downstream process analytic technology (PAT) and quality by design (QbD) within the context of batch vs. continuous chromatography. The ...

WEST LAFAYETTE, Ind. — International process systems and operation experts have launched high-tech startup Crystallization Systems Technology Inc. (CrySyst) to streamline processes used by companies ...

Currently, bioprocess monitoring and control systems rely on infrequent and time-consuming offline sampling methods. This can lead to loopholes in data and major gaps in knowledge, as well as ...

Scale-up involves increasing pump sizes, reactor volumes, and flow rates—but the process control logic and system ...

At the heart of this approach is the integration of real-time analytical techniques with process control systems, a capability that underpins both PAT and Quality by Design (QbD) frameworks. In this ...

On-line analyzers are of growing importance for process monitoring, optimization, and control of numerous large-scale applications across the refining, petrochemical, power generation, metals, and ...

Increasingly tight tolerances and rigorous demands for quality are forcing chipmakers and equipment manufacturers to ferret out minor process variances, which can create significant anomalies in ...

Editor’s note: This article is the third in a series to help practitioners learn about the AICPA’s new quality management standards and prepare to implement them. The new final standards on quality ...