Identification of non-coding regions that control gene expression, like CHASERR, is one way her team is thinking about using their knowledge of the human genome to design gene-targeting therapies.

Cellular homeostasis and stress response are tightly coordinated processes involving a complex interplay between signaling pathways and gene expression regulation. Both transcriptional and ...

Long non-coding RNAs (lncRNA) are a type of RNA molecule that do not carry instructions to make proteins. Instead, they influence how other genes are expressed. There are tens of thousands of lncRNAs ...

Osteoarthritis (OA) is the most common age-related joint disorder, affecting more than 500 million people worldwide and representing a leading cause of ...