No statistically significant change in MADRS total score was observed with solriamfetol vs placebo in the overall study population. Topline results were announced from a phase 3 trial evaluating ...

The use of 42 mg lumateperone combined with antidepressant therapy was linked to significantly reduced severity of depression and anxiety, as well as greater response and remission rates, and was ...

The approval of medicines called second-generation antipsychotics has allowed major depressive disorder (MDD) and other conditions linked to it to be treated. A person with MDD is usually prescribed ...

Experts recommended individualized MDD relapse prevention, including ECT tapering and pharmacotherapy based on risk profiles.

A study published in the Journal of Affective Disorders proposes a novel, fully automated artificial intelligence (AI) algorithm leveraging ExtraTrees (ET) forests to distinguish patients with major ...

In addition to ADHD and MDD, Axsome also is investigating Sunosi as a treatment for binge eating disorder and excessive sleepiness associated with shift work disorder. Given its novel mechanism of ...

The largest and most ethnically diverse study of its kind has identified 697 genetic variants linked to major depressive disorder (MDD). The research also highlights potential therapies for ...

Zachary Contreras of Sharp Health Plan discusses how predictive tools, artificial intelligence-driven analytics, and digital monitoring can help identify treatment-resistant depression early, enabling ...