Methotrexate is one of the oldest and most cost-effective medicines available for rheumatoid arthritis (RA). Its also one of the most commonly used RA therapies. Heres what to know about this drug if ...

Compared with placebo, low-dose methotrexate administered weekly at doses up to 15 mg for 52 weeks did not relieve knee pain or reduce the size of effusion-synovitis in patients with inflammatory knee ...

High-dose methotrexate (HDMTX) is an antineoplastic dosing strategy used to treat various cancers including primary central nervous system lymphoma. Trimethoprim-sulfamethoxazole (TMP/SMX) is commonly ...