产生新德里金属β-内酰胺酶（NDM）的碳青霉烯类耐药大肠杆菌（CREC）对全球公共卫生构成了严重威胁。及时检测CREC对于有效管理患者和控制耐药性的传播至关重要。 目的 本研究旨在利用基质辅助激光解吸电离飞行时间质谱（MALDI-TOF MS）结合机器学习（ML）技术 ...

血清IGF-1检测中MALDI-TOF MS与CLIA的一致性研究：纳入660名0-90岁健康人群，通过线性回归（R2=0.982）、ICC（>0.80）及Bland-Altman分析，证实MALDI-TOF MS与CLIA在IGF-1检测中具有高度一致性，为建立统一参考范围奠定基础。 胰岛素样生长因子I（IGF-1）对生长、代谢和细胞增殖 ...

MALDI-TOF MS yields absolute molecular weights not relative ones. MALDI-TOF MS is a fast and versatile method to address challenges in the synthesis or quality control of polymers. Structural features ...

A laser-based instrument developed by the analytical equipment supplier Bruker is to be used in rapid screening of hospital patients for signs of antibiotic-resistant diseases. The company's ...

Nail psoriasis is common in patients with plaque psoriasis and is associated with morbidity, including onychomycosis, which can complicate psoriasis treatments and be difficult to differentiate.

It's been 20 years since Hillenkamp and Karas developed MALDI. In that time, the soft ionization method, coupled with time-of-flight (TOF) mass spectrometry, has distinguished itself as the enabling ...

Inching towards precision medicine for multiple myeloma with causal network models. This is an ASCO Meeting Abstract from the 2019 ASCO Annual Meeting I. This abstract does not include a full text ...

Matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF) mass spectrometry has become, in recent years, a tool of choice for large-molecule analyses, especially for proteins. Published ...

Recently developed Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry (MALDI-TOF-MS) requires innovative methods for designing automated liquid handling systems. An overview ...