Biopharmaceuticals, medium- and high-molecular weight biologically active macromolecules, are not easily absorbed by the small intestine, the main organ responsible for gastrointestinal absorption, ...

Biopharmaceuticals, medium- and high-molecular weight biologically active macromolecules, are not easily absorbed by the small intestine, the main organ responsible for gastrointestinal absorption, ...

Orally administered drugs have to pass through the gut wall mucosa before they may reach the capillaries that lead to the portal vein. This barrier consists of polarized enterocytes that are closely ...

The d-xylose absorption test is useful in the diagnosis of tropical and idiopathic sprue, 1–4 but results are variable in other disorders and in elderly persons without intestinal disease. 5,6 ...

New research shows that certain flavonols from everyday foods can shut down the body’s drug-resistance machinery, potentially paving the way for more effective treatments, but clinical hurdles remain.

Although the liver is not a major site of de novo cholesterol synthesis, it plays a central role in regulating plasma LDL-C levels. [12] This occurs because the liver is the principal site for both ...

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The way in which the body processes cholesterol affects the risk of cardiovascular diseases. LDL cholesterol is obtained from ...

In this interview, Karl Box discusses how particle drift analysis using flux tools improves oral drug absorption in pharmaceutical research. Can you tell us about Pion’s Rainbow Dynamic Dissolution ...