The innate immune system serves as the body's first line of defence, rapidly detecting and responding to external pathogens and internal damage. Recent advances in the field have highlighted the ...

Innate immune sensors – known as pattern recognition receptors (PRRs) – detect specific molecular components of bacterial or viral intruders. The PRRs forward the signals which results in the ...

Innate lymphoid cells, which curiously behave like T cells even though they don’t recognize specific antigens, show promise as a potential cancer therapeutic. In the years that followed, other groups ...

From Left to Right: Iñaki Robles-Vera, David Sancho, Vanesa Núñez, Manuel Rodrigo-Tapias, Sarai Martínez-Cano, Marcos Femenía-Muiña, Ana Redondo-Urzainqui, Aitor Jarit-Cabanillas, Manuel J. Gomez, Ana ...

Unlike transient innate immune activation, trained immunity is characterized by long-lasting but reversible functional reprogramming of monocytes, macrophages, natural killer (NK) cells, and ...

Researchers have discovered that mRNA-based COVID-19 vaccines have a persistent effect on the innate immune system. These mechanisms may help the human body to better protect itself against potential ...