2026年4月17日，北京大学博雅讲席教授、昌平实验室领衔科学家、生命科学学院邓宏魁课题组在国际学术期刊《细胞》（Cell）上发表了题为“p53 safeguards chemical reprogramming of human somatic cells toward pluripotency”的研究论文。该研究发现，关键肿瘤抑制因子p53在化学重编程中发挥核心保护作用，打破了“p53阻碍细胞 ...

Paper in Cloning and Stem Cells shows that animal eggs do not support specific reprogramming toward the normal human embryonic state. Investigators at Advanced Cell Technology (ACTC) have found that ...

Studies on diseases that affect the human brain are usually based on animal models which cannot reproduce the complexity of human neuropathies. Therefore, these methodologies often fail when applied ...

Scientists have produced stem cells from the endangered Grévy's zebra using human reprogramming factors. Further comprehensive gene analyses identified key genes that are also found in human and mouse ...

Scientists from Kyoto University’s Institute for Integrated Cell-Material Sciences (iCeMS) and Wildlife Research Centre have produced stem cells from the endangered Grévy’s zebra using human ...

Zhou’s study, "TBX20 improves contractility and mitochondrial function during direct human cardiac reprogramming," was recently published in Circulation. The most common cause of death worldwide is ...

Scientists report that they have used a cellular reprogramming methodology to allow the creation of neural networks that reproduce unique characteristics of human cells—different from those obtained ...

Mammalian hearts have almost no ability to grow new heart muscle cells, called cardiomyocytes, after birth. Thus, dead tissue after an adult heart attack is not repaired with new cardiomyocytes. It is ...