Understanding the interplay between T cells and B cells is pivotal to delineating both protective immunity and the pathogenesis of autoimmune diseases. Central to this dynamic are specialised CD4⁺ T ...

For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor cell ...

During infections, the immune system needs to distinguish foreign antigens that are expressed by invading bacteria and viruses from self-antigens that are expressed by cells of the body. If not, the ...

CD4+ T cells, long regarded as supporting actors in cancer immunity, are emerging as central regulators of tumor control and ...

A study shows dietary fat balance can alter the lipid composition of T cells, influencing their survival, antibody support, ...

During infections, the immune system needs to distinguish foreign molecules from invading bacteria and viruses from molecules that are made by cells of the body. If it can’t, the immune system can ...

There are two types of Tph cells in rheumatoid arthritis joints that have different roles. Stem-like Tph cells live inside immune “hubs” called tertiary lymphoid structures, where they interact ...

The types of fats we consume directly impacts the survival and strength of the body's immune cells and ability to fight ...

Researchers at the University of Michigan have revealed that cells use a previously unknown feat of molecular craftsmanship to help protect their larger host organisms. The building blocks required ...