HMGA2 is a non-histone chromatin-binding protein that has emerged as a critical regulator in both cancer progression and stem cell biology. Frequently overexpressed in various malignancies, HMGA2 ...

This review highlights the critical role of ubiquitination in governing the functionality of cancer stem cells (CSCs), shedding light on potential therapeutic targets for combating tumor progression, ...

Scientists at University of California San Diego have developed a new approach to destroying cancer stem cells – hard-to-find cells that help cancers spread, come back after treatment and resist ...

Researchers from University of California San Diego Sanford Stem Cell Institute have discovered that spaceflight accelerates the aging of human hematopoietic stem and progenitor cells (HSPCs), which ...

Scientists at University of California, San Diego (UCSD), have developed a new approach to destroying cancer stem cells (CSCs)—the hard-to-find cells that help cancers spread, come back after ...

Researchers mapped distinct cancer cell communities within supratentorial ependymoma tumors, showing how different cell types drive tumor growth, mobility, and interactions with the brain environment.

Swallowing is a fundamental human function that supports nutrition and communication. Damage to swallowing muscles can reduce ...

Cancer scientists have been working against the clock for decades to outsmart a disease that comes back more powerfully after treatment. Traditional treatments like chemotherapy, radiation, and even ...

In a first-of-its-kind clinical trial, UCLA scientists have shown it's possible to reprogram a patient's blood-forming stem cells to generate a continuous supply of functional T cells, the immune ...