AlphaGenome 能够一次性分析多达 100 万个 DNA 碱基对，预测突变如何干扰基因的调控方式，如何改变其激活时机、在体内哪些细胞中表达，以及其生物调控开关是处于高或低的状态。来源 Nature来源 卫报翻译 科研圈bot1 月 28 日，谷歌 DeepMind 以《自然》（Nature）封面文章形式推出其最新人工智能（AI）工具 ...

传统认知中，MYC是驱动癌细胞无限增殖的“总开关”——它作为转录因子，结合在DNA上，对大量基因的表达产生积极影响，形成肿瘤的特征性表达谱。除此之外，MYC还可以帮助癌细胞逃避免疫系统的监视：在胰腺癌模型中，敲除MYC能引发肿瘤消退，但这种效应在免疫 ...

Although there are striking differences between the cells that make up your eyes, kidneys, brain and toes, the DNA blueprint ...

DNA, the blueprint of life, is best known for its fundamental role as genetic material—storing and transmitting biological information through the precise sequence of its bases. For decades, this ...

Scientists have long suspected connections between heredity and disease, dating back to Hippocrates, who observed certain diseases ‘ran in families’. However, through the years, scientists have kept ...

Zettabytes—that’s 10 21 bytes—of data are currently generated every year. All of those cat videos have to be stored somewhere, and DNA is a great storage medium; it has amazing data density and is ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...

Scientists have uncovered new DNA-binding proteins from some of the most extreme environments on Earth and shown that they ...