Guarding genes against damage is a crucial and complex job, so it’s to be expected that cells have several mechanisms to repair DNA breakages, each providing support under different circumstances. For ...

DNA repair is essential for the maintenance of genomic stability and its failure can lead to human disease. Various DNA repair systems exist, such as base excision repair, nucleotide excision repair, ...

Researchers have discovered how a metabolite involved in repairing damaged DNA not only controls a person’s sensitivity to cancer therapies but can also protect healthy tissues from damage. The ...

A powerful new discovery reveals that Nup98 a protein once thought to only ferry molecules through the nucleus plays a vital role in safeguarding the most vulnerable areas of DNA. By forming ...

Two teams of researchers have uncovered microscopic details of how a protein called photolyase uses light to repair DNA. The discovery could help develop sustainable technologies for chemical ...

A protein found in our cells has emerged as a secret weapon against biological aging, acting like a glue to repair damaged DNA and ward off neurological degeneration including that seen in motor ...

Cryogenic electron microscopy (cryo-EM) has enabled researchers to study how the DNA replication machinery assembles at sites where DNA is damaged. Cellular DNA is continuously exposed to both ...

Francesca Storici consults at Tessera Therapeutics. She has received funding from the National Institutes of Health and the National Science Foundation. Your DNA is continually damaged by sources both ...

A repair system in our cells fixes DNA damage caused by exposure to ultraviolet (UV) light from the sun, however the detailed process behind this is not fully understood. An international research ...

Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to switch genes on and off with exquisite precision. The latest work on ...

Shape shifts happen all around you. Cells stretch, tissues curl, and living structures shift their form as naturally as breathing. Scientists have tried to copy those abilities for years, hoping to ...