Breakthrough in CRISPR: HKUST scientists engineered a DNA-guided Cas12a system that targets and cleaves RNA with unprecedented precision. Practical advantages: DNA guides are cheaper, more stable, and ...

A new review article published in Genes & Diseases explores the intricate relationship between non-coding RNAs and oxidative stress in cancer progression shedding new light on the mechanisms that ...

When a gene produces too much protein, it can have devastating consequences on brain development and function. Patients with an overproduction of protein from the chromodomain helicase DNA binding ...

Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...

Plant molecular evolution offers key insights into how coding and regulatory changes shape the diversity of form and function across the plant kingdom. The ...

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are linked to many diseases. Until now, the genetic basis ...

Cellular homeostasis and stress response are tightly coordinated processes involving a complex interplay between signaling pathways and gene expression regulation. Both transcriptional and ...

Johns Hopkins researchers have shown that disrupting energy metabolism in tumor cells can slow the growth of group 3 medulloblastoma, a highly aggressive pediatric brain cancer, in mice. The study ...