The space between the arachnoid and pia meningeal layers encasing the brain is a landscape of connective tissue, blood vessels, and cerebrospinal fluid. Scientists debate how that fluid moves within ...

The typical signs and symptoms of idiopathic NPH are shown. In a retrospective study involving 418 patients with shunt-responsive idiopathic NPH, 96% of the patients had gait difficulty, 76% had ...

A novel blood and cerebrospinal fluid (CSF) measure showed promise as a biomarker for Parkinsonian disorders. CSF levels of DOPA decarboxylase (DDC) -- an enzyme that converts levodopa into dopamine - ...

With age, the brain’s ability to clear aggregating proteins such as Aβ wanes. In the November 9 Nature, researchers led by Jonathan Kipnis at Washington University in St. Louis suggest a reason why.

A test measuring proteins in spinal fluid may help support the diagnosis of MS, especially in patients whose disease is harder to diagnose.

Bagged in three layers of meninges and selectively fenced off by the blood brain barrier, our central nervous system (CNS) interacts within strict limits with our immune system. Protective ...

Approximately 400,000 cases of infantile and childhood hydrocephalus occur worldwide annually. 1 For most affected patients, treatment is inadequate because of limited access to care. Left untreated, ...