The space between the arachnoid and pia meningeal layers encasing the brain is a landscape of connective tissue, blood vessels, and cerebrospinal fluid. Scientists debate how that fluid moves within ...

The typical signs and symptoms of idiopathic NPH are shown. In a retrospective study involving 418 patients with shunt-responsive idiopathic NPH, 96% of the patients had gait difficulty, 76% had ...

Chiari malformation type I (CMI) is a congenital neurological disorder characterized by the herniation of cerebellar tonsils through the foramen magnum, leading to impaired cerebrospinal fluid (CSF) ...

Approximately 400,000 cases of infantile and childhood hydrocephalus occur worldwide annually. 1 For most affected patients, treatment is inadequate because of limited access to care. Left untreated, ...

A novel blood and cerebrospinal fluid (CSF) measure showed promise as a biomarker for Parkinsonian disorders. CSF levels of DOPA decarboxylase (DDC) -- an enzyme that converts levodopa into dopamine - ...