Bone tissue is a complex structure, consisting of mineralized collagen fibers and a variety of non-collagenous proteins, including proteoglycans such as biglycan and decorin. These proteoglycans ...

Around 500 million years ago, early vertebrates in the seas became fish, adopting an inner skeleton and a flexible spine based on a nanocmposite of fibers and mineral, known as bone material. This ...

A recent study has uncovered the essential roles of two proteoglycans, biglycan and decorin, in maintaining bone mass, water retention, and bulk/in situ mechanical competence. Through the use of ...

Fat inside bones is turning out to be far more dangerous than anyone expected. A new study published in Bone Research ...

Obesity alters bone health not only through increased body weight but also by reshaping the bone marrow environment.

How Bone Marrow Fat Drives Immune Suppression And Bone Loss In Obesity. EINPresswire/ -- Researchers reveal how bone marrow fat reprograms immune signaling to promote osteoclast activity and weaken bo ...