H5_fold-0_Chantal, H5_fold-0_Elsa, H6_fold-C_Rei, H6_fold-Z_Gogy, H6_fold-U_Nomur, and H7_fold-K_Mussoc are presented. For each de novo designed protein, the computational model is shown on the left, ...

A team of US researchers has gained new insights into how large protein molecules consistently fold themselves into useful shapes. Using a new approach to fluorescence microscopy, Hoi Sung Chung and ...

University of Missouri researchers have released the world's largest collection of protein models with quality assessment—a groundbreaking new resource that could accelerate drug development for ...

In the wee hours of an October morning, David Baker, a protein biologist at the University of Washington (UW), received the most-awaited phone call in a scientist’s career. Halfway around the world, ...

Computational models show that even subtle modifications in the synaptic protein CaMKII completely alter the resulting protein structures. Given how the formation and stability of these structures ...

David Baker, Demis Hassabis and John M. Jumper shared the Nobel Prize in Chemistry on Wednesday for their work on protein structure. Atila Altuntas / Anadolu via Getty Images On Wednesday morning, ...

With MassiveFold, scientists have unlocked AlphaFold's full potential, making high-confidence protein predictions faster and more accessible, fueling breakthroughs in biology and drug discovery. Brief ...

A new computer process makes it possible to generate active pharmaceutical ingredients quickly and easily based on a protein's three-dimensional surface. The new process could revolutionize drug ...